Autophagy is a natural cellular cleaning program. Damaged molecules and organelles are enveloped by vesicles, enzymatically upcycled and then reused. Impaired autophagy weakens the skin barrier and promotes skin “garb-ageing”.
Autophagy - a cellular upcycling plant
REFORCYL®-AION triggers vesicle formation by disassembly of the Golgi apparatus, the cellular parcel service. Furthermore, it maintains mitochondrial health and promotes their fusion to form an energy-rich network. It also upregulates the LC3 gene that is responsible for the fusion with lysosome, the enzymatic waste degradation system.
Scientifically confirmed effects:
- Induces autophagy by upregulation of LC3A (in-vitro study)
- "Spring cleans" to produce healthy cells and strengthens mitochondria under stressed conditions (in-vitro study)
- Provides an upcycled look to ageing skin (in-vivo study)
Clinical studies have shown that activating this form of cellular spring-cleaning markedly improves skin tone and leads to smooth, redensified skin.
Sustainable production and recycling
REFORCYL®-AION is climate-neutral and conforms to the principles of circular economy. It is based on the press cake of organically grown Styrian oil pumpkin seeds, a residual product of oil pressing and is part of a closed production loop.
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