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Garb'Ageing Clean-Up

REFORCYL®-AION is a cosmetic upcycling concept combining cutting-edge molecular findings about autophagy with principles of circular economy and carbon-neutrality.
It rejuvenates and purifies the skin by activating the key parameters of a healthy autophagy process: Golgi vesicle formation, mitochondrial fitness and LC3 gene upregulation.
Autophagy is a natural cellular cleaning program. Damaged molecules and organelles  are enveloped by vesicles, enzymatically upcycled and then reused. Impaired autophagy weakens the skin barrier and promotes skin “garb-ageing”.

Autophagy - a cellular upcycling plant


REFORCYL®-AION triggers vesicle formation by disassembly of the Golgi apparatus, the cellular parcel service. Furthermore, it maintains mitochondrial health and promotes their fusion to form an energy-rich network. It also upregulates the LC3 gene that is responsible for the fusion with lysosome, the enzymatic waste degradation system.

Scientifically confirmed effects:

  • Induces autophagy by upregulation of LC3A (in-vitro study)
  • "Spring cleans" to produce healthy cells and strengthens mitochondria under stressed conditions (in-vitro study)
  • Provides an upcycled look to ageing skin (in-vivo study) 

Clinical studies have shown that activating this form of cellular spring-cleaning markedly improves skin tone and leads to smooth, redensified skin.

Sustainable production and recycling

REFORCYL®-AION is climate-neutral and conforms to the principles of circular economy. It is based on the press cake of organically grown Styrian oil pumpkin seeds, a residual product of oil pressing and is part of a closed production loop.


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Click here to get to the REFORCYL®-AION site and download more documents.