The pain receptor TRPV1, which is expressed in the epidermis’ sensory neurons and keratinocytes, regulates the skin’s comfort zone:
Elevated levels of TRPV1 may lead to increased skin sensitivity and unpleasant sensations caused by e.g. sunburn or chemical peelings.
On the other hand, heat stress, particularly caused by IR-light, can activate TRPV1, which, in turn, induces typical ageing processes such as enhanced collagen degradation. This modern form of pre-mature skin ageing caused by heat stress is also known as “thermal ageing”.
RAHN’s brand-new DEFENSIL®-SOFT is a neuro-balm from A to Zen which blocks TRPV1 and upgrades the skin’s comfort zone. The active ingredient is based on the edible mushroom Albatrellus ovinus, also called the Northern truffle.
DEFENSIL®-SOFT is conform to COSMOS and Ecocert.
Applied on the skin, it provides zen-like soothing and anti-ageing effects:
- Reduces skin discomfort and irritation within minutes
- Increases the heat-pain tolerance of normal and ultra-sensitive skin
- Prevents IR-ageing by protecting from IR-induced heat stress
- Improves skin’s tolerance towards irritants in cosmetic formulations
Click here to get to the DEFENSIL®-SOFT site and download more documents.
Do you want to learn more about the TRPV1 receptor? Just watch our video: